个人介绍：

田宇，2013年本科毕业于中国药科大学，获得药物制剂学士学位；2016年毕业于中国药科大学，获得药剂学硕士学位；2020年博士毕业于荷兰格罗宁根大学（导师：Henderik W. Frijlink），获博士学位。2020年11月-2023年11月于上海交通大学医学院附属仁济医院上海市肿瘤研究所任助理研究员；2023年11月加入上海大学医学院。主要从事纳米药物递送系统、微针经皮递药系统的研究。以第一作者（含共同第一）在J. Control. Release, Adv. Healthc. Mater., ACS Appl. Mater. Inter., Expert Opin. Drug Deliv. 等国际权威期刊发表SCI论文10余篇。主持国家自然科学基金青年基金，上海市科委扬帆计划等。申请发明专利2项，授权专利1项。

主要研究领域：

1 抗肿瘤药物纳米递送系统联合肿瘤免疫治疗

2 微针经皮递药系统

3 蛋白多肽类药物和疫苗递送系统的研究

代表性学术成果：

论文（最具代表性）

[1] Y. Tian, H. Jing, Q. Wang, et al. Dissolving microneedles-based programmed delivery system for enhanced chemo-immunotherapy of melanoma. J Control Release (IF=11.467) 2023; 360:630-646.

[2] Y. Tian, G. Mi, Q. Chen, et al. Acid-induced activated cell-penetrating peptide-modified cholesterol-conjugated polyoxyethylene sorbitol oleate mixed micelles for pH-triggered drug release and efficient brain tumor targeting based on a charge reversal mechanism. ACS Appl Mater Interfaces (IF= 10.383) 2018; 10: 43411-43428.

[3] Q. Wang^#, Y. Tian^#, L. Liu^#, C. Chen, et al. Precise targeting therapy of orthotopic gastric carcinoma by siRNA and chemotherapeutic drug codelivered in pH‐sensitive nano platform. Adv Healthc Mater. (IF= 11.092) 2021; 10:2100966.

[4] Yu Tian, Jiangtao Lin, Hongshu Jing, et al. Recent progress in orodispersible films-mediated therapeutic applications: a review. MedComm – Biomaterialsand Applications. 2023; 2:e34.

[5] Y. Tian, J. Lee, K van der Maaden, et al. Intradermal administration of influenza vaccine with trehalose and pullulan-based dissolving microneedle arrays. J Pharm Sci. (IF=3.8) 2022; 111:1070-1080.

[6] Y. Tian, Y.C. Bhide, H.J. Woerdenbag, et al. Development of an orodispersible film containing stabilized influenza vaccine. Pharmaceutics. (IF= 6.525) 2020; 12:245.

[7] Y. Tian, M. Orlu, H.J. Woerdenbag, et al. Oromucosal films: from patient centricity to production by printing techniques. Expert Opin Drug Deliv. (IF= 8.129) 2019; 16: 981-993.2019; 16: 981-993.

[8] Y. Tian, J.C. Visser, J.S. Klever, et al. Orodispersible films based on blends of trehalose and pullulan for protein delivery. Eur J Pharm Biopharm (IF= 5.589) 2018; 133: 104-111.

[9] Y. Tian, Y. Shen, M. Jv. Synthesis, characterization and evaluation of tinidazole-loaded mPEG-PDLLA (10/90) in situ gel forming system for periodontitis treatment. Drug Deliv. (IF=6.819) 2016; 23(8):2726-2735.

社会学术兼职：

上海市药学会药剂学专委会基础药剂学组组员、世界中医药学会联合会经皮给药专委会会员、Eur J Pharm Biopharm，Int. J. Pharm.杂志审稿人。