个人介绍：
田宇，硕士生导师，2013年本科毕业于中国药科大学，获得药物制剂学士学位；2016年毕业于中国药科大学，获得药剂学硕士学位；2020年博士毕业于荷兰格罗宁根大学（导师：Henderik W. Frijlink教授），获博士学位。2023年11月加入上海大学医学院。主要从事纳米药物递送系统、微针经皮递药系统的研究。以第一作者/通讯作者（含共同）在Adv. Funct. Mater., J. Control. Release, Chem. Eng. J., Carbohydr. Polym. 等国际权威期刊发表SCI论文20余篇。主持国家自然科学基金青年基金，上海市自然科学基金，上海市科委扬帆计划等。申请发明专利2项，授权专利1项。
主要研究领域：
1.抗肿瘤药物纳米递送系统联合肿瘤免疫治疗
2.微针经皮递药系统
3.蛋白多肽类药物和疫苗递送系统的研究
代表性学术成果：
论文（最具代表性）
[1] Y. Tian, L. Xia, X. Song, Yu Chen. Dissolving microneedles as in situ chemical reaction chambers: from design strategies to versatile biomedical applications. Adv. Funct. Mater. (IF=19.0) 2025; 35, 2422274.
[2] Y. Tian, H. Jing, Q. Wang, et al. Dissolving microneedles-based programmed delivery system for enhanced chemo-immunotherapy of melanoma. J Control Release (IF=11.5) 2023; 360:630-646.
[3] Y. Tian, B. Chang, Z. Zong, J. Wang, X. Lu, Y. Li, Q. Zheng, R. Wei, Y. Shen, Y. Chen. Guanidine grafted chitosan oligosaccharides polymers promoting GLUT-mediated gastrointestinal barrier transport for potentiating Fe3O4 mineralized probiotics in obesity treatment. Carbohydr. Polym. (IF=12.5) 2025; 366, 123918.
[4] X. Gu, J. Liu, H. Xiang, R. Liao, Y. Ge, D. Damdinjav, B. Dorjsuren, T. Hao, D. Chen, Y. Tian*, Y. Shen*. Fixed-point cleaved bioinspired nanosystem via promoting LAT1-mediated BBB penetration for spatiotemporal therapy in TMZ resistant glioblastoma. Chem. Eng. J. (IF=13.2) 2025; 517, 164470.
[5] Y. Tian, G. Mi, Q. Chen, et al. Acid-induced activated cell-penetrating peptide-modified cholesterol-conjugated polyoxyethylene sorbitol oleate mixed micelles for pH-triggered drug release and efficient brain tumor targeting based on a charge reversal mechanism. ACS Appl Mater Interfaces (IF= 8.2) 2018; 10: 43411-43428.
[6] Q. Wang#, Y. Tian#, L. Liu#, C. Chen, et al. Precise targeting therapy of orthotopic gastric carcinoma by siRNA and chemotherapeutic drug codelivered in pH‐sensitive nano platform. Adv Healthc Mater. (IF= 10.0) 2021; 10:2100966.
[7] Y. Tian, J. Lee, K van der Maaden, et al. Intradermal administration of influenza vaccine with trehalose and pullulan-based dissolving microneedle arrays. J Pharm Sci. (IF=3.8) 2022; 111:1070-1080.
[8] Y. Tian, Y.C. Bhide, H.J. Woerdenbag, et al. Development of an orodispersible film containing stabilized influenza vaccine. Pharmaceutics (IF= 5.5) 2020; 12:245.
[9] Y. Tian, M. Orlu, H.J. Woerdenbag, et al. Oromucosal films: from patient centricity to production by printing techniques. Expert Opin Drug Deliv. (IF= 5.4) 2019; 16: 981-993.2019; 16: 981-993.
[10] Y. Tian, J.C. Visser, J.S. Klever, et al. Orodispersible films based on blends of trehalose and pullulan for protein delivery. Eur J Pharm Biopharm (IF= 4.3) 2018; 133: 104-111.
[11] Y. Tian, Y. Shen, M. Jv. Synthesis, characterization and evaluation of tinidazole-loaded mPEG-PDLLA (10/90) in situ gel forming system for periodontitis treatment. Drug Deliv. (IF=8.1) 2016; 23(8):2726-2735.
社会学术兼职：
上海市药学会药剂学专委会青年委员、世界中医药学会联合会经皮给药专委会会员、Eur J Pharm Biopharm，Int. J. Pharm.杂志审稿人。
