个人介绍

       高明春，2017年毕业于上海大学，获工学博士学位。2018年，赴美国加州大学戴维斯分校(UCD)做博士后研究。2021年回国入职上海大学医学院。

主要研究领域

       药物化学、有机合成方法学

代表性学术成果

论文

1. Mingchun Gao, Yingying Li, Yuansheng Gan, and Bin Xu, “Copper Nitrate Mediated Regioselective [2+2+1] Cyclization of Alkynes with Alkenes: A Cascade Approach to Δ2- Isoxazolines” Angew. Chem. Int. Ed. 2015, 54, 8795.  

2. Mingchun Gao, and Bin Xu, “Copper Nitrate-Mediated Regio- and Stereoselective Difunctionalization of Alkynes: A Direct Approach to α-Chloro-β-nitroolefins” Org. Lett. 2016, 18, 4746.

3. Mingchun Gao, and Bin Xu, “Transition Metal-Involving Synthesis and Utilization of N- containing Heterocycles: Exploration of Nitrogen Sources” Chem. Rec. 2016, 16, 1701.

4. Yingying Li,† Mingchun Gao,† Bingxin Liu, and Bin Xu, “Copper Nitrate-Mediated Chemo- and Regioselective Annulation from Two Different Alkynes: A Direct Route to Isoxazoles” Org. Chem. Front. 2017, 4, 445.

5. Mingchun Gao, Rongxuan Ye, Weijia Shen, and Bin Xu, “Copper nitrate: A privileged reagent for organic synthesis” Org. Biomol. Chem. 2018, 16, 2602.

6. Mingchun Gao, Minfen Zou, Jue Wang, Qitao Tan, Bingxin Liu, and Bin Xu, “Palladium- Catalyzed Multicomponent Reaction of Alkynes, Carboxylic Acids, and Isocyanides: A Direct Approach to Captodative Olefins” Org. Lett. 2019, 21, 1593.

7. Mingchun Gao, Kaijing Zhou, and Bin Xu, “Copper Nitrate-Mediated Selective Difunctionalization of Alkenes: A Rapid Access to β-Bromonitrates” Adv. Synth. Catal. 2019, 361, 2031.

8. Mingchun Gao,† Yuansheng Gan,† and Bin Xu, “From Alkenes to Isoxazolines via Copper- Mediated Alkene Cleavage and Dipolar Cycloaddition” Org. Lett. 2019, 21, 7435.

9. Bowen Shen,† Mingchun Gao,† Francisco C. Franco, Jr., Rohan Kapre, Junhan Zhou, Xinzhe Li, Joel Garcia, Jared T. Shaw, and Angelique Y. Louie, “Effect of Structure and Intramolecular Distances on Photoswitchable Magnetic Resonance Imaging Contrast Agents” J. Org. Chem. 2020, 85, 7333.

10. Mingchun Gao,† Bowen Shen,† Junhan Zhou, Rohan Kapre, Angelique Y. Louie, and Jared T. Shaw, “Synthesis and Comparative Evaluation of Photoswitchable Magnetic Resonance Imaging Contrast Agents” ACS Omega 2020, 5, 14759.