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陈雪瑞

创建时间:  2020-06-24  孙湛蓉   浏览次数:   返回


个人介绍

       陈雪瑞,2019年毕业于浙江大学获得理学博士学位,同年进入上海大学医学院任讲师。至今已在ACS Applied Materials & Interfaces, Biomaterials Science, Langmuir, ACS Biomaterials Science & Engineering, RSC Advances, Colloids and Surfaces B: Biointerfaces., Colloids and Surfaces A: Physicochemical and Engineering Aspects.等SCI收录的期刊上发表12篇论文。主持一项国家自然科学基金青年项目(22003038)。


主要研究领域

1. 肿瘤微环境响应型纳米递药系统的构建与靶向功能修饰;

2. 抗肿瘤药物的靶向释放与协同治疗;

3. 生物热力学及微量热学。


代表性学术成果

论文

1. Chen, X.R.; Tong, R.L.; Shi, Z.Q.; Yang, B.; Liu, H.; Ding, S.P.; Wang, X.; Lei, Q.F.; Wu, J.*; Fang, W.J*. MOF Nanoparticles with Encapsulated Autophagy Inhibitor in Controlled Drug Delivery System for Antitumor. ACS Appl. Mater. Interfaces, 2018, 10 (3), 2328-2337.(高被引论文)

2. Chen, X.R.#; Tong, R.L.#; Liu, B.B.; Liu H.; Feng X.D.; Ding, S.P.; Lei, Q.F.; Tang, G.P.; Wu, J.*; Fang, W.J.* Duo of (–)-Epigallocatechin-3-Gallate and Doxorubicin Loaded by Polydopamine Coating ZIF-8 in Regulation of Autophagy for Chemo-Photothermal Synergistic Therapy. Biomater. Sci., 2020, 8(5), 1380-1393.

3. Chen, X.R.; Shi, Z.Q.; Tong, R.L.; Ding, S.P.; Wang, X.; Wu, J.; Lei, Q.F.*; Fang, W.J.* Derivative of Epigallocatechin-3-gallatea Encapsulated in ZIF-8 with Polyethylene Glycol–Folic Acid Modification for Target and pH-Responsive Drug Release in Anticancer Research. ACS Biomater. Sci. Eng. 2018, 4 (12), 4183-4192.  

4. Chen, X.R.#; Liu, B.B.#; Tong, R.L.; Ding, S.P.; Wu, J.; Lei, Q.F.*; Fang, W.F.* Improved Stability and Targeted Cytotoxicity of Epigallocatechin-3-Gallate Palmitate for Anticancer Therapy. Langmuir, 2021, 37(2), 969-977.

5. Chen, X.R.#; Liu, B.B.#; Tong, R.L; Zhan, L.; Yin, X.L.; Luo, X.; Huang, Y.N.; Zhang, J.F.; He, W.; Wang, Y.L.* Orchestration of Biomimetic Membrane Coating and Nanotherapeutics in Personalized Anticancer Therapy. Biomaterials Science, 2021, 9(3), 590-625.

6. Chen, X.R.; Zhang, L.; Ding, S.P.; Lei, Q.F.*; Fang, W.J.* Cisplatin Combination Drugs Induce Autophagy in HeLa Cells and Interact with HSA via Electrostatic Binding Affinity. RSC Advances, 2017, 7, 22270-22279.

7. Shi, Z.Q.; Chen, X.R.; Zhang, L.; Ding, S.P.; Wang, X.; Lei, Q.F.*; Fang, W.J.* FA-PEG Decorated MOF Nanoparticles as a Targeted Drug Delivery System for Controlled Release of an Autophagy Inhibitor. Biomaterials Science 2018, 6, 239-240.

8. Zhang, S.S.; Chen, X.R.; Yu, J.; Hong, B.Y.; Lei, Q.F.*; Fang, W.J.* Hydrophobic Fractal Surface from Glycerol Tripalmitate and the Effects on C6 Glioma Cell Growth. Colloids and Surfaces B-Biointerfaces. 2016, 142, 377-384.

9. Zhang, S.S.; Chen, X.R.; Ding, S.P.; Lei, Q.F.*; Fang, W.J.* Unfolding of Human Serum Albumin by Gemini and Single-chain Surfactants: A Comparative Study. Colloids and Surfaces A-Physicochemical and Engineering Aspects. 2016, 495, 30-38.

10. Zhang, L.; Chen, X.R.; Wu, J.Z.; Ding, S.P.; Wang, X.; Lei, Q.F. *; Fang, W.J.* Palladium Nanoparticles Induce Autophagy and Autophagic Flux Blockade in Hela Cells. RSC Advances, 2018, 8, 4130.




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