个人介绍
谢雨洁，副教授，上海市海外高层次人才。本科和硕士毕业于兰州大学化学系(导师：唐瑜教授)。2016年于英国华威大学高分子化学专业开展博士的研究工作（导师：Rachel O’Reilly）。2020年至2021年在英国伯明翰大学进行博士后的研究工作。于2022年1月加入上海大学医学院，承担上海市海外高层次领军人才项目、国家自然科学基金青年基金、国家科技部外专项目等。目前共发表文章50余篇，以第一作者/通讯作者（含共同）身份在国际著名期刊发表SCI论文20余篇，包括国际主流学术期刊Adv. Mater., Nat. Commun., Angew. Chem. Int. Ed, Chem. Soc. Rev., Adv. Sci., Macromolecules, Biomacromolecules, J. Mater. Chem. B, Chem. Commun., Macromol. Rapid. Commun.等。另外以合作者身份在Nat. Chem.、J. Am. Chem. Soc.、Nat. Commun.、Adv. Mater.、Angew. Chem. Int. Ed、Chem. Sci.等期刊发表论文30余篇，申请国家发明专利8项。担任Adv. Mater., Angew. Chem. Int. Ed.，Adv. Healthc. Mater, ACS Appl. Mater. Interfaces等期刊独立审稿人。
主要研究领域
1、高分子基的智能药物载体设计、肿瘤纳米疫苗开发；
2、二维、三维高分子基生物医用材料。
代表性学术成果
论文（最具代表性）
[1] Huijing Wang, Wenjin He, Jing Liao, Shuangshuang Wang, Xinyue Dai, Meihua Yu*, Yujie Xie*, Yu Chen*, Catalytic Biomaterials-Activated In Situ Chemical Reactions: Strategic Modulation and Enhanced Disease Treatment. Adv. Mater. 2025, 37, 2411967.
[2] Wencong Jia, Ye Wu, Yujie Xie*, Meihua Yu*, Yu Chen*, Advanced Polymeric Nanoparticles for Cancer Immunotherapy: Materials Engineering, Immunotherapeutic Mechanism and Clinical Translation. Adv. Mater. 2025, 2413603.
[3] Yujie Xie, Zaizai Tong, Tianlai Xia, Joshua C. Worch, Julia Y. Rho, Rachel K. O’Reilly*, Andrew P. Dove*, 2D Hierarchical Microbarcodes with Expanded Storage Capacity for Optical Multiplex and Information Encryption, Adv. Mater. 2024, 36, 2308154.
[4] Jake E. Barker, Joshua D. Tibbetts, Calum T. J. Ferguson, Yujie Xie*, Rachel K. O'Reilly*, Substituted Maleimides: Self-Reportable Linkers and Tags in Bioconjugation, Materials Science, and Nanotechnology Angew. Chem. Int. Ed. 2024, e202410550.
[5] Xinyue Dai, Yujie Xie*, Wei Feng*, Yu Chen*, Nanomedicine-enabled chemical regulation of reactive X species for versatile disease treatments, Angew. Chem.Int. Ed..2023, e202309160
[6] Yujie Xie, Maria C. Arno, Jonathan T. Husband, Miquel Torrent-Sucarrat, Rachel K. O’Reilly* Manipulating the Fluorescence Lifetime at The Sub-cellular Scale via Photo-switchable Barcoding. Nat. Commun. 2020, 11, 2460 Editor’s Highlight
[7] Ran Tao, Huijing Wang, Ruijie Hou, Bowen Zheng, Yidan Zhao, Yujie Xie*, Zaizai Tong, Program the “Light-Flashable” 2D Fluorescent Lifetime Microbarcodes for Precision Information Storage, Adv. Funct. Mater. 2025, 2500737
[8] Hongze Ren, Anqi Zhu, Wei Yang, Yiwen Jia, Hui Cheng, Ye Wu, Zhengqi Tang, Weifan Ye, Mayu Sun, Yujie Xie*, Meihua Yu*, Yu Chen*, 2D Differential Metallic Immunopotentiators Drive High Diversity and Capability of Antigen-specific Immunity Against Tumor. Adv. Sci. 2024, 2405729
[9] Anqi Zhu, Hongze Ren, Xiaolong Li, Wei Yang, Xiaoxia Han, Xiaodong Hou, Shen Zhang, Shaoyue Li, Yujie Xie*, Meihua Yu*, Yu Chen*, Huixiong Xu*, Transdermal STING nano-agonists enhance multifaced functions of antigen-specific T cells triggered by sonodynamic cancer vaccination. Nanotoday. 2025, 61, 102590
[10] Meng Chen, Lili Xia, Chenyao Wu, Zeyu Wang, Li Ding*, Yujie Xie*, Wei Feng*, Yu Chen* Microbe-material hybrids for therapeutic applications Chem. Soc. Rev., 2024, 53, 8306
[11] Hongze Ren, Wencong Jia, Yujie Xie*, Meihua Yu*, Yu Chen*, Adjuvant physiochemistry and advanced nanotechnology for vaccine development, Chem. Soc. Rev., 2023, 52, 5172-5254
[12] Kexing Li, Shuangshuang Wang, Chunmei Chen, Yujie Xie*, Xinyue Dai*, Yu Chen*, Sonocatalytic biomaterials, Coord. Chem. Rev., 522, 216242
[13] Yujie Xie, Wei Yu, Tianlai Xia, Rachel K. O’Reilly * Andrew P. Dove*, Stereocomplex-driven morphological transition (SDMT) of coil-rod-coil poly(lactic acid)-based cylindrical nanoparticles, Macromolecules, 2023, 56, 19, 7689-7697.
[14] Bingbing Xiang, Xiang Wang, Feiyang Teng, Liping Liu, Meili Li, Xiancheng Meng, Zhenyan Chu, Xianjing Zhou*, Yujie Xie* Zaizai Tong*, Regulation of Two-Dimensional Platelet Micelles by Dynamic Changing of Polymer Topological Architectures upon Light Irradiation, Macromolecules, 2023, 56, 9685-9696
[15] Sang Guangze, Wang Bingkai*, Yujie Xie*, Chen Yu*, Yang Feng*, Engineered Probiotic-Based Biomaterials for Inflammatory Bowel Disease Treatment. Theranostics 2025; 15(8):3289-3315.
[16] Xu Zhang, Guanhao Chen, Bowen Zheng, Zhengwei Wan, Liping Liu, Lingyuan Zhu, Yujie Xie*, and Zaizai Tong*, Uniform two-dimensional crystalline platelets with tailored compositions for pH stimulus-responsive drug release, Biomacromolecules 2023, 24, 1032-1041
