个人介绍
高娟，副教授。2012年博士毕业于复旦大学与法国斯特拉斯堡大学；2012年11月进入上海大学生命科学学院工作；2019年11月进入上海大学医学院工作。工作期间作为项目负责人承担国家自然基金青年项目、面上项目、上海市自然基金面上项目各1项，也参与了多项国家自然基金面上项目、重大研究计划与重大项目的研究工作；已发表科研论文30余篇。
主要研究领域
1. 血小板功能调控和心血管病的发生机制研究
2. 运动保护心力衰竭的作用与机制研究
代表性学术成果
论文
1. Zhan Qingyi; Peng Wenjing; Wang Siqi; Gao Juan*; Heart Failure with Preserved Ejection Fraction: Pathogenesis, Diagnosis, Exercise, and Medical Therapies. Journal of Cardiovascular Translational Research, 2023, 16(2):310-326.
2. Liu Qi; Chen Liyang; Liang Xuchun; Cao Yuqing; Zhu Xinyue; Wang Siqi; Li Jin; Gao Juan*; Xiao Junjie*; Exercise attenuates angiotensin II-induced muscle atrophy by targeting PPARγ/miR-29b, Journal of Sport and Health Science, 2022, 11(6):696-707.
3. Gao Juan#; Lu Yi#; Gokulnath Priyanka; Vulugundam Gururaja; Li Guoping; Li Jin, Xiao Junjie*; Benefits of physical activity on cardiometabolic diseases in obese children and adolescents, Journal of Translational Internal Medicine, 2022,10(3): 236-245.
4. Gao Juan, Pan Xue, Li Guoping, Chatterjee E, Xiao Junjie*. Physical Exercise Protects Against Endothelial Dysfunction in Cardiovascular and Metabolic Diseases. Journal of Cardiovascular Translational Research. 2022, 15(3):604-620.
5. Zhou Qiulian#, Bai Yuzheng#, Gao Juan#, Duan Yi, Lyu Yicheng, Guan Lonfei, Elkin Kenneth, Xie Yuling, Jiao Zheng*, Wang Hongyun*. Human Serum-derived Extracellular Vesicles Protect A549 from PM 2.5-induced Cell Apoptosis. Biomedical and Environmental Sciences, 2021, 34(1):40-49.
6. Cheng Huiling#; Wu Xiaodong#; Ni Gehui; Wang Siqi; Peng Wenjing; Zhang Haifeng*; Gao Juan*; Li Xinli*; Citri reticulatae pericarpium protects against isoproterenol-induced chronic heart failure via activation of PPARγ, Annals of Translational Medicine, 2020, 8(21): 1396.
7. Yan Yan#; Xu Ying#; Ni Gehui; Wang Siqi; Li Xinli*; Gao Juan*; Zhang Haifeng*; MicroRNA-221 promotes proliferation and migration of pulmonary arterial smooth muscle cells (PASMCs) by targeting tissue inhibitor of metalloproteinases-3 (TIMP3), Cardiovascular Diagnosis and Therapy, 2020,10(4): 646-657.
8. Gao Juan; Bao Yun; Ge Shushu; Sun Peisen; Sun Jiaojiao; Liu Jianmin; Chen Feng; Han Li; Cao Zhongyuan; Qin Jun; White C. Gilbert; Xu Zhen*; Ma Yan-Qing*; Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1, Cell Communication and Signaling, 2019,17(1): 101.
9. Gao Juan; Huang Ming; Lai Jingjing; Mao Kaijun; Sun Peisen; Cao Zhongyuan; Hu Youpei; Zhang Yingying; Schulte Marie L; Jin Chaozhi; Wang Jian; White Gilbert C; Xu Zhen*; Ma Yanqing*, Kindlin supports platelet integrin alphaIIbbeta3 activation by interacting with paxillin. Journal of cell science, 2017, 130(21):3764-3775.
10. Xu Zhen; Cai Jiayi; Gao Juan; White Gilbert C; Chen Fangyuan; Ma Yanqing, Interaction of kindlin-3 and beta2-integrins differentially regulates neutrophil recruitment and NET release in mice. Blood, 2015, 126, 373-377.
11. Zhou Wangbin; Gao Juan; Ma Jing; Cao Lin; Zhang Chi; Zhu Yan; Dong Aiwu*; Shen Wenhui*, Distinct roles of the histone chaperones NAP1 and NRP and the chromatin-remodeling factor INO80 in somatic homologous recombination in Arabidopsis thaliana. Plant Journal, 2016, 88, 397–410
12. Gao Juan; Zhu Yan; Zhou Wangbin; Molinier Jean; Dong Aiwu; Shen Wenhui; NAP1 family histone chaperones are required for somatic homologous recombination in Arabidopsis. Plant Cell, 2012, 24(4):1437-1447.
